Impact of a Ketogenic Food regimen versus a Mediterranean Food regimen on HbA1c in People with Prediabetes and Kind 2 Diabetes Mellitus: the Interventional Keto-Med Randomized Crossover Trial
Proper off the bat, I do not like that they studied each diabetes and prediabetics. There have been solely 40 authentic examine individuals, with full knowledge on solely 33. Why lump the 2 collectively?
Individuals adopted every weight loss program for 12 weeks then lab knowledge and physique weight have been assessed.
The researchers conclusions:
HbA1c [a measure of blood sugar control] was not totally different between weight loss program phases after 12-weeks, however improved from baseline on each diets, probably attributable to a number of shared dietary elements. WFKD [ketogenic diet] was helpful for larger lower in triglycerides, but additionally had potential untoward dangers from elevated LDL-C, and decrease nutrient intakes from avoiding legumes, fruits, and entire intact grains, in addition to being much less sustainable.
Triglycerides dropped extra on the keto weight loss program, no shock. Physique weight dropped the identical for each diets, 7-8%. HDL-cholesterol (the “good ldl cholesterol”) rose 11% on keto and seven% on the Mediterranean weight loss program. HgbA1c dropped the identical on each diets, about 8% from baseline. Each diets result in consuming ~300 energy much less per day than baseline consumption.
Dr Bret Scher addressed the elevated LDL-cholesterol (aka “unhealthy ldl cholesterol”) over at DietDoctor.com:
The authors reported that LDL “dangerously” rose 10% on the keto weight loss program. However was it actually a harmful change? Triglycerides went down on the keto weight loss program, as we’d count on. And as we noticed in 2018 with the Virta Well being trial, on common, LDL went up 10%. Nonetheless, the calculated cardiac danger rating went down 12%.
By way of answering the headline query, Keto Versus Mediterranean Food regimen: Which Is Greatest for T2 Diabetics and Prediabetics?, the reply actually is determined by long-term knowledge regarding longevity and numerous illnesses. This examine would not reply the query.
What say you?
Steve Parker, MD
